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KMID : 0665220170300020251
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Korean Journal of Food and Nutrition
2017 Volume.30 No. 2 p.251 ~ p.256
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Fatty Acid Composition and Anti-inflammatory Effects of the Freeze Dried Tenebrio molitor Larva
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Kang Mi-Sook
Kim Min-Ju
Han Jung-Soon
Kim Ae-Jung
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Abstract
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This study aimed to assess fatty acid composition and anti-inflammatory effects, such as nitric oxide(NO) production, expression of TNF-α and interleukin-6(IL-6), of Tenebrio molitor larva using RAW 264.7 cells. The content of total fatty acid in Tenebrio molitor larva was 76.14%, which was composed of oleic acid(42.12%), linoleic acid(32.67%) etc. There was no cytotoxicity at a dose level of 0.1, 1.0, 10, and 100 μg/mL of freeze dried Tenebrio molitor larva ethanol extract(FDTEtOH) on RAW 264.7 cells. FDTEtOH significantly decreased NO production in LPS(lipopolysaccharide)- stimulated RAW 264.7 cells in a dose-dependent manner. Also, FDTEtOH dose-dependently suppressed the expression of TNF- α and IL-6. Thus, these results showed that Tenebrio molitor larva has the potential to be used as an anti-inflammatory food to improve immunity.
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KEYWORD
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Tenebrio molitor larva, fatty acid composition, anti-inflammatory effects
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